Salaita Lab

DNA-based Digital Tension Probes Reveal Early Cell Adhesion Mechanics at the Single Molecule Level
Nature Communications, 5, 5167, 2014.
Zhang, Y.; Ge, C.; Zhu, C.; Salaita, K.

[SI movie 1] [SI movie 2] [SI movie 3] [SI movie 4].

See research feature in Nature Reviews Molecular and Cell Biology See research feature in Nature Methods See research feature in C&E News See research feature in Emory eScienceCommons

Nanoparticle Tension Probes Patterned at the Nanoscale: Impact of integrin clustering on force transmission
Nano Letters, 14(10), 5539-5546, 2014. 
Liu, Y.; Medda, R.; Liu, Z.; Galior, K.; Yehl, K.; Cavalcanti-Adam, A. E.; Spatz, J.; Salaita, K.; “”,

[SI movie 1] [SI movie 2] [SI movie 3]

Integrin-generated Forces Lead to Streptavidin-Biotin Unbinding in Cellular Adhesions
Biophysical Journal, 106(7), 1436-1446, 2014.
Jurchenko, Carol; Chang, Yuan; Narui, Yoshie; Zhang, Yun; Salaita, Khalid 

[SI movie 1] [SI movie 2].

See highlight in April 7th, 2014 issue of C&E News: http://cen.acs.org/articles/92/i14/Cellular-TugWar.html

Structurally Defined Nano-scale Sheets from Self-Assembly of Collagen-Mimetic Peptides
Journal of the American Chemical Society, 136(11), 4300-4308, 2014.
Jiang, T.; Xu, C.; Liu, Y.; Liu, Z.; Wall S. J.; Zuo, X.; Lian, T.; Salaita, K.; Ni, C.; Pochan, D.; Conticello, V., P.

Quantum dots encapsulated within phospholipid membranes: phase-dependent structure, photostability, and site-selective functionalization
Journal of the American Chemical Society, 136(5), 1992–1999, 2014.
Zheng, Weiwei; Liu, Yang; West, Ana; Schuler, Erin; Yehl, Kevin; Dyer, R.; Kindt, James; Salaita, Khalid

 [SI movie 1] 

The modulation of cardiac progenitor cell function by hydrogel-dependent Notch1 activation
Biomaterials, 35(28), 8103-8112, 2014.
Boopathy, A. V.; Che, P. L.; Somasuntharam I., Fiore V. F.; Cabigas, E. B.; Ban, K.; Brown M. E.; Narui, Y.; Barker T. H.; Yoon, Y.; Salaita, K.; García, A. J.; Davis, M. E.

Membrane Tethered Delta Activates Notch and Reveals a Role for Spatio-Mechanical Regulation of the Signaling Pathway
Biophysical Journal, 105(12), 2655-2665, 2013.
Narui, Y.; Salaita, K.

[SI movie 1] [SI movie 2]

Tension Sensing Nanoparticles for Mechano-imaging at the Living Non-living Interface
Journal of the American Chemical Society, 135(14), 5320–5323, 2013.
Liu, Y.; Yehl, K.; Narui, Y.; Salaita, K.

 [movie 1] [movie 2]

Manipulating the Lateral Diffusion of Surface-Anchored EGF Demonstrates that Receptor Clustering Modulates Phosphorylation Levels
Integrative Biology, 5, 659-668, 2013.
Stabley, D.; Retterer, S.; Marshall, S.; Salaita, K.

[movie 1] [movie 2] [movie 3]

Visualizing Mechanical Tension Across Membrane Receptors with a Fluorescent Sensor
Nature Methods, 9, 64-67, 2012.
Stabley, D.; Schumacher, C.; Marshall, S.; Salaita, K.

See interview in Nature Methods[nmeth.1816.pdf]

See also C&E news highlight: [C&ENews] [C&E News video]

[youtube]

Catalytic Deoxyribozyme-Modified Nanoparticles for RNAi-Independent Gene Regulation
ACS Nano, 6(10), 9150–9157, 2012.
Yehl, K.; Joshi, J.P.; Greene, B.L.; Dyer, R. B.; Nahta, R.; Salaita, K.

The Molecular Boat: A Hands-on Experiment to Demonstrate the Forces Applied to Self-Assembled Monolayers at Interfaces
Journal of Chemical Education, 89(12), 1547–1550, 2012.
Chan, C.; Salaita, K. 

Dip-pen Nanolithography of Optically Transparent Cationic Polymers to Manipulate Spatial Organization of Proteolipid Membranes"
Chemical Science, 3, 794-799, 2012.
Narui, Y.; Salaita, K.